Of the 28 trials I read, twelve were young trials (published <5 years), six were middle aged and ten were classic old timers. We reviewed seven pieces regarding medical education and reviewed one set of guidelines (stroke prevention 2024). Compared to last year, I read more trials and less editorials.
I continue to search for an optimal balance of classic appraisal vs challenging dogma. I have also found myself less moved by the articles on humanity and wonder if that is a symptom of a growing cynicism from old age.
Content-wise, when compared to last year, I reviewed less GLP-1 trials yet they continue to become a standard of care for more diseases. This is on my mind because I recently visited Oklahoma to visit family and literally all of my aunts and uncles (five in total) were on some form of GLP1. The uptake has been unprecedented. I worry guidelines will not be able to keep up with the sheer volume of evidence being published.
For the month of July, I will choose papers that shaped how I think about medicine in the spirit new crop of interns.
(07/07/2025) Week 161